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Test Code LAB316 HEPARIN LEVEL, LOW MOLECULAR WEIGHT (LMWH)

Method

Chromogenic Anti Xa Assay

CPT(s)

Description CPT  Code
Heparin Level Low Molecular Weight 85520

 

Specimen Information

Container Specimen Temperature Collect Vol Submit Vol Min Vol Stability
Blue Top Tube Plasma Frozen To fill line 1 mL plasma 1 mL plasma 6 months
Blue Top Tube Whole Blood Ambient To fill line To fill line To fill line 75 minutes

TUBE MUST BE FULL AT COLLECTION. Whole blood should remain at ambient temperature until processed. Refer to Coagulation Specimen Handling  prior to collection.  Double spin before freezing-see Coag Spec Processing step 3.  Submit 2 × 0.5 mL frozen plasma aliquots for this test. Draw blood in light blue top tube(s). Spin down, remove plasma, spin plasma again and  place citrate platelet-poor plasma in the required number of plastic vials (Glass vials cannot be accepted.)  Freeze specimen at ≤ -40° C if possible.  Send specimen frozen on dry ice. Each coagulation assay requested should have one tube per test.

Reference Range

THERAPEUTIC HEPARIN RANGE
(for twice-a-day dosing, peak sample drawn 4 hours post subcutaneous injection) for treatment of venous thromboembolism: Adults and children: 0.5 – 1.1 IU/mL Newborn: 0.5 - 1.0 IU/mL
 

(for once-a-day dosing, peak sample drawn 4 hours post subcutaneous injection) for treatment of venous thromboembolism: 1.0 – 2.0 IU/mL Patient sample tested against Low Molecular Weight heparin – Results may not be reliable for unfractionated heparin, pentassacharide (Fondaparinux) or Danaparoid (ORGARAN).

Instrumentation

ACL Top 

Performing Location

University of Vermont Medical Center

UVMHN-Porter Medical Center Note:

Performed at PMC LAB

Test Schedule / Analytical Time / Test Priority

Daily / 24 Hours / Available STAT

Section

Coagulation

Is the UVMMC lab NY State Certified to perform this testing?  Yes/No

Yes